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Browse Mutations ampDD135N

GeneampD

Anhydro-N-acetylmuramyl tripeptide amidase

Protein ChangeD135N

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: change in amino acid
Resistance To: beta lactams
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.

PMID 12384343 · 2002

Mutations in ampD and ampR lead to increased beta-lactam resistance

Mutation Information

Protein Change: D135N
Organisms: Pseudomonas aeruginosa
Confers Resistance To: beta lactams
Effect on Function: change in amino acid
Validation Method: sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research