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Browse Mutations parEP424Q

GeneparE

Protein ChangeP424Q

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: confers resistance
Resistance To: ciprofloxacin
Organisms: Streptococcus mitis, Streptococcus pneumoniae
Papers: 1

Paper Information1

1

Fluoroquinolone resistance mutations in the parC, parE, and gyrA genes of clinical isolates of viridans group streptococci.

PMID 9797205 · 1998

A novel sense mutation affecting the ParE subunit

Mutation Information

Protein Change: P424Q
Organisms: Streptococcus mitis, Streptococcus pneumoniae
Confers Resistance To: ciprofloxacin
Effect on Function: confers resistance
Validation Method: sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research