ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeA168V

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: aminoglycosides|fluoroquinolones|carbapenems
Papers: 1

Paper Information1

Multiple mutations lead to MexXY-OprM-dependent aminoglycoside resistance in clinical strains of Pseudomonas aeruginosa.

PMID 24145539 · 2014

Mutations in parRS lead to overexpression of mexXY and decreased OprD expression, resulting in resistance to aminoglycosides, fluoroquinolones, and carbapenems.

Mutation Information

parRS: p.A168V

Protein Change: A168V
Confers Resistance To: aminoglycosides|fluoroquinolones|carbapenems
Validation Method: sequence analysis
Source Database: Reslit

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