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Browse Mutations gyrAT83C

GenegyrA

Nucleotide ChangeT83C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: nalidixic acid
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Increased mutagenesis in starving bacteria does not explain the increased frequency of antibiotic-resistant mutants

PMID 24244205 · 2013

The S83L mutation in gyrA was found to confer a slight increase in mutant to wildtype ratio in aging colonies.

Mutation Information

Nucleotide Change: T83C
Organisms: Escherichia coli
Confers Resistance To: nalidixic acid
Validation Method: competition experiments and Sanger re-sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research