ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeR507G

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReslit

Overview

Mechanism: single resistance variant
Resistance To: ethambutol
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Mutations in the embB gene and their association with ethambutol resistance in multidrug-resistant Mycobacterium tuberculosis clinical isolates from Poland.

PMID 24392447 · 2013

Only mutations in codons 406 and 507 were found exclusively in EMB-resistant isolates.

Mycobacterium tuberculosis embB mutant conferring resistance to ethambutol; CARD accession: CARD:3003326

Mutation Information

embB: p.R507G

Protein Change: R507G
Organisms: Mycobacterium tuberculosis
Confers Resistance To: ethambutol
Effect on Function: single resistance variant
Validation Method: sequencing and comparison with reference strain
Source Database: ReslitCard Database

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