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Browse Mutations gyrBR492C

GenegyrB

Protein ChangeR492C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ciprofloxacin|moxifloxacin
Organisms: Mycobacterium abscessus, Mycobacterium massiliense
Papers: 1

Paper Information1

1

The drug resistance profile of Mycobacterium abscessus group strains from Korea.

PMID 24422193 · 2014

Mutation at amino acid position 492 (Arg→Cys) in the gyrB gene is associated with resistance to ciprofloxacin and moxifloxacin.

Mutation Information

Protein Change: R492C
Organisms: Mycobacterium abscessus, Mycobacterium massiliense
Confers Resistance To: ciprofloxacin|moxifloxacin
Validation Method: PCR and sequence analysis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research