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Browse Mutations gyrAE92K

GenegyrA

Protein ChangeE92K

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: alterations in topoisomerase IV
Resistance To: ciprofloxacin|nalidixic acid
Organisms: Salmonella enterica
Papers: 1

Paper Information1

1

Antimicrobial resistance in Salmonella enterica Serovar Typhi isolates from Bangladesh, Indonesia, Taiwan, and Vietnam.

PMID 25136011 · 2014

Mutations in gyrA and parC contribute to quinolone resistance.

Mutation Information

Protein Change: E92K
Organisms: Salmonella enterica
Confers Resistance To: ciprofloxacin|nalidixic acid
Effect on Function: alterations in topoisomerase IV
Validation Method: characterization of nalidixic acid and ciprofloxacin resistance mechanisms in isolates from Bangladesh
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research