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Browse Mutations pbp2bT624G

penicillin-binding protein 2B

Protein ChangeT624G

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: resistance
Resistance To: imipenem
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

1

Complete sequences of six penicillin-binding protein genes from 40 Streptococcus pneumoniae clinical isolates collected in Japan.

PMID 15155228 · 2004

observed in 18 of 19 strains

Mutation Information

Protein Change: T624G
Organisms: Streptococcus pneumoniae
Confers Resistance To: imipenem
Effect on Function: resistance
Validation Method: sequencing and MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research