ResLit - Antimicrobial Resistance Gene & Mutation Database

GenepmrB

Protein ChangeP344L

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: colistin
Organisms: Klebsiella pneumoniae
Papers: 1

Paper Information1

The Occurence of Colistin-Resistant Hypervirulent Klebsiella pneumoniae in China.

PMID 30410479 · 2018

Cloning of pmrB encoding the P344L substitution into a colistin-susceptible K. pneumoniae strain did not alter MICs of colistin, suggesting that such a substitution did not confer resistance to colistin.

Mutation Information

pmrB: p.P344L

Protein Change: P344L
Organisms: Klebsiella pneumoniae
Confers Resistance To: colistin
Validation Method: cloning of pmrB encoding the P344L substitution into a colistin-susceptible K. pneumoniae strain
Source Database: Reslit

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