ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeR140H

Nucleotide ChangeG419A

Validation StatusCandidate

Databases

Reslit

Overview

Paper Information2

Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan.

Mutations in the pncA gene were identified in PZA-resistant isolates.

Gibbs Free Energy Calculation of Mutation in PncA and RpsA Associated With Pyrazinamide Resistance.

Protein Change: R140H
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: molecular dynamics simulation and Gibbs free energy calculation
Source Database: Reslit

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