ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeG78S

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReslit

Overview

Mechanism: single resistance variant
Resistance To: pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 2

Paper Information2

Overcoming the pitfalls of automatic interpretation of whole genome sequencing data by online tools for the prediction of pyrazinamide resistance in Mycobacterium tuberculosis.

PMID 30817803 · 2019

Mutations in pncA were associated with pyrazinamide resistance.

Mutation Information

pncA: p.G78S

Protein Change: G78S
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: Sanger sequencing
Source Database: Reslit

PMID 978-92-4-008241-0

Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide; CARD accession: CARD:3003394

Mutation Information

pncA: p.G78S

Protein Change: G78S
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Effect on Function: single resistance variant
Source Database: Card Database

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