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Browse Mutations parEP451S

GeneparE

Protein ChangeP451S

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: DNA topoisomerase IV subunit B ParE
Resistance To: fluoroquinolones, quinolones
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

In Vitro and In Vivo Activity of Zabofloxacin and Other Fluoroquinolones Against MRSA Isolates from A University Hospital in Egypt.

PMID 31050254 · 2019

Mutation Information

Protein Change: P451S
Organisms: Staphylococcus aureus
Confers Resistance To: fluoroquinolones
Validation Method: PCR amplification and sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research