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Browse Mutations lexAS119A

GenelexA

LexA repressor

Protein ChangeS119A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ciprofloxacin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Induction and inhibition of ciprofloxacin resistance-conferring mutations in hypermutator bacteria.

PMID 16377689 · 2006

LexA cleavage is required for the evolution of ciprofloxacin resistance.

Mutation Information

Protein Change: S119A
Organisms: Escherichia coli
Confers Resistance To: ciprofloxacin
Validation Method: mutation of Ser119 to Ala
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research