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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

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Browse Mutations katGD137S

GenekatG

Protein ChangeD137S

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: isoniazid
Papers: 1

Paper Information1

1

The pathogenic mechanism of Mycobacterium tuberculosis: implication for new drug development.

PMID 36547804 · 2022

S315T mutation reduces INH affinity

Mutation Information

Protein Change: D137S
Confers Resistance To: isoniazid
Validation Method: structural analysis and mutagenesis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research