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Browse Mutations gyrBA4650G

GenegyrB

Nucleotide ChangeA4650G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: levofloxacin
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Pseudomonas aeruginosa heteroresistance to levofloxacin caused by upregulated expression of essential genes for DNA replication and repair.

PMID 36620018 · 2022

The nonsynonymous SNP in gyrB was not associated with heteroresistance of PAS81 strain.

Mutation Information

Nucleotide Change: A4650G
Organisms: Pseudomonas aeruginosa
Confers Resistance To: levofloxacin
Validation Method: whole-genome sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research