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Browse Mutations parER586W

GeneparE

Protein ChangeR586W

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ciprofloxacin
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Parallel Evolution to Elucidate the Contributions of PA0625 and parE to Ciprofloxacin Sensitivity in Pseudomonas aeruginosa.

PMID 36677304 · 2022

The ParE R586W substitution does not contribute to resistance but confers tolerance against ciprofloxacin.

Mutation Information

Protein Change: R586W
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ciprofloxacin
Validation Method: gene editing and ciprofloxacin susceptibility assay
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research