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Browse Mutations nalDT158P

GenenalD

Protein ChangeT158P

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: regulator of the MexAB-OprM efflux pump
Resistance To: ceftazidime, aztreonam
Organisms: Pseudomonas aeruginosa
Papers: 2

Paper Information2

1

Ceftazidime resistance in Pseudomonas aeruginosa is multigenic and complex.

PMID 37192202 · 2023

Mutation Information

Protein Change: T158P
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ceftazidime
Effect on Function: regulator of the MexAB-OprM efflux pump
Validation Method: cloning in P. aeruginosa + MIC testing
Source Database: Reslit

2

Evolved Aztreonam Resistance Is Multifactorial and Can Produce Hypervirulence in Pseudomonas aeruginosa.

PMID 29089424 · 2017

Mutation Information

Protein Change: T158P
Organisms: Pseudomonas aeruginosa
Confers Resistance To: aztreonam
Validation Method: whole-genome sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research