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Browse Mutations gyrAG616S

GenegyrA

Protein ChangeG616S

Nucleotide ChangeG1846A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: delafloxacin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Resistance development in Escherichia coli to delafloxacin at pHs 6.0 and 7.3 compared to ciprofloxacin.

PMID 37882542 · 2023

Mutations in gyrA were seen in all derivatives challenged with CIP, regardless of pH.

Mutation Information

gyrA: p.G616S / c.G1846A

Protein Change: G616S
Nucleotide Change: G1846A
Organisms: Escherichia coli
Confers Resistance To: delafloxacin
Validation Method: complementation assay
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research