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Browse Mutations parCA117V

GeneparC

Protein ChangeA117V

Nucleotide ChangeC350T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: delafloxacin|ciprofloxacin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Resistance development in Escherichia coli to delafloxacin at pHs 6.0 and 7.3 compared to ciprofloxacin.

PMID 37882542 · 2023

Mutations at the A117 site were common in both DLX- and CIP-challenged strains.

Mutation Information

parC: p.A117V / c.C350T

Protein Change: A117V
Nucleotide Change: C350T
Organisms: Escherichia coli
Confers Resistance To: delafloxacin|ciprofloxacin
Validation Method: complementation assay
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research