ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeS105I

Validation StatusCandidate

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Reslit

Overview

Resistance To: ciprofloxacin
Organisms: Escherichia coli
Papers: 1

Paper Information1

Resistome and virulome of high-risk pandemic clones of multidrug-resistant extra-intestinal pathogenic Escherichia coli (ExPEC) isolated from tertiary healthcare settings in Uganda.

PMID 37992119 · 2023

Mutation Information

gyrA: p.S105I

Protein Change: S105I
Organisms: Escherichia coli
Confers Resistance To: ciprofloxacin
Validation Method: chromosomal point mutations within the gyrA gene responsible for ciprofloxacin resistance phenotype were detected in 82.1% of the isolates. The observed change in nucleotide was from TCG to "TTG/GTG" in the isolates detected with gyrA mutation ( S1 File )
Source Database: Reslit

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