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Browse Mutations dltX1del

GenedltX

Protein Change1del

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: increased susceptibility to polymyxin B
Resistance To: polymyxin b
Organisms: Streptococcus pyogenes
Papers: 1

Paper Information1

1

The Dlt and LiaFSR systems derepress SpeB production independently in the Δpde2 mutant of Streptococcus pyogenes.

PMID 38029265 · 2023

Deletion of dltX increases susceptibility to polymyxin B.

Mutation Information

Protein Change: 1del
Organisms: Streptococcus pyogenes
Confers Resistance To: polymyxin b
Effect on Function: increased susceptibility to polymyxin B
Validation Method: MIC measurement
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research