ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeS95A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: levofloxacin|moxifloxacin, ofloxacin|moxifloxacin
Organisms: Mycobacterium tuberculosis
Papers: 2

Paper Information2

Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach.

PMID 38216576 · 2024

mutations

Mutation Information

gyrA: p.S95A

Protein Change: S95A
Organisms: Mycobacterium tuberculosis
Confers Resistance To: levofloxacin|moxifloxacin
Source Database: Reslit

Sequence Analysis of Fluoroquinolone Resistance-Associated Genes gyrA and gyrB in Clinical Mycobacterium tuberculosis Isolates from Patients Suspected of Having Multidrug-Resistant Tuberculosis in New Delhi, India.

PMID 27335153 · 2016

Heterozygous mutations were observed in 4/27 (14.8%) mutations.

Mutation Information

gyrA: p.S95A / c.A283G

Protein Change: S95A
Nucleotide Change: A283G
Confers Resistance To: ofloxacin|moxifloxacin
Validation Method: sequencing
Source Database: Reslit

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