ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeD79N

Validation StatusSupported

Databases

Reslit

Overview

Resistance To: ciprofloxacin, fluoroquinolones, enrofloxacin
Organisms: Salmonella enterica, Mycoplasma synoviae
Papers: 3

Paper Information3

Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes.

PMID 19917752 · 2010

Mutation Information

parC: p.D79N

Protein Change: D79N
Organisms: Salmonella enterica
Confers Resistance To: ciprofloxacin
Validation Method: PCR amplification and sequencing
Source Database: Reslit

Molecular resistance mechanisms to newly approved antibiotics (2017-2025) in WHO priority pathogens.

PMID 41608681 · 2025

Mutation Information

parC: p.D79N

Protein Change: D79N
Confers Resistance To: fluoroquinolones
Validation Method: linked to reduced clinical efficacy in trial settings
Source Database: Reslit

Molecular characterization of acquired enrofloxacin resistance in Mycoplasma synoviae field isolates.

PMID 23612192 · 2013

Mutation Information

parC: p.D79N

Protein Change: D79N
Organisms: Mycoplasma synoviae
Confers Resistance To: enrofloxacin
Validation Method: sequencing and MIC testing
Source Database: Reslit

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