ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeN57K

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene CatalogReslit

Overview

Mechanism: single resistance variant, DNA gyrase subunit A GyrA
Resistance To: nalidixic acid|norfloxacin, fluoroquinolones, quinolones
Organisms: Shigella flexneri, Escherichia coli
Papers: 1

Paper Information1

Novel mutations in quinolone resistance-determining regions of gyrA, gyrB, parC and parE in Shigella flexneri clinical isolates from eastern Chinese populations between 2001 and 2011.

PMID 27620866 · 2016

Shigella flexneri gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003940

Mutation Information

gyrA: p.N57K

Protein Change: N57K
Organisms: Shigella flexneri
Confers Resistance To: nalidixic acid|norfloxacinfluoroquinolones
Effect on Function: single resistance variant
Validation Method: sequencing
Source Database: ReslitCard Database

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