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ResLit

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Browse Mutations pncAA156G

GenepncA

Protein ChangeA156G

Nucleotide ChangeC468G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Signatures of Selection at Drug Resistance Loci in Mycobacterium tuberculosis.

PMID 29404424 · 2018

major PZA resistance mutation

Mutation Information

pncA: p.A156G / c.C468G

Protein Change: A156G
Nucleotide Change: C468G
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: whole-genome sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research