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Browse Mutations katGL499M

GenekatG

Protein ChangeL499M

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: isoniazid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Modeling the structural origins of drug resistance to isoniazid via key mutations in Mycobacterium tuberculosis catalase-peroxidase, KatG.

PMID 29523317 · 2018

Mutations in katG associated with isoniazid resistance

Mutation Information

Protein Change: L499M
Organisms: Mycobacterium tuberculosis
Confers Resistance To: isoniazid
Validation Method: structural modeling
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research