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ResLit

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Browse Mutations gyrBD500G

GenegyrB

Protein ChangeD500G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fluoroquinolones
Papers: 1

Paper Information1

1

Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains.

PMID 29755957 · 2018

Mutations in the QRDR of gyrB are less common but still contribute to FQ resistance.

Mutation Information

Protein Change: D500G
Confers Resistance To: fluoroquinolones
Validation Method: experimental validation
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research