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Browse Mutations ftsIY528H

GeneftsI

Protein ChangeY528H

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ampicillin|amoxicillin
Organisms: Haemophilus influenzae, Escherichia coli
Papers: 1

Paper Information1

1

A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility.

PMID 29855260 · 2018

The wild-type ftsI gene was susceptible to aminopenicillins.

Mutation Information

Protein Change: Y528H
Organisms: Haemophilus influenzae, Escherichia coli
Confers Resistance To: ampicillin|amoxicillin
Validation Method: site-directed mutagenesis and broth microdilution
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research