ResLit - Antimicrobial Resistance Gene & Mutation Database

Genepbp2b

penicillin-binding protein 2B

Protein ChangeG435S

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: penicillin
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

Whole genome sequencing of penicillin-resistant Streptococcus pneumoniae reveals mutations in penicillin-binding proteins and in a putative iron permease.

PMID 22108223 · 2011

Mutation Information

pbp2b: p.G435S

Protein Change: G435S
Organisms: Streptococcus pneumoniae
Confers Resistance To: penicillin
Validation Method: transformation and MIC testing
Source Database: Reslit

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