ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeT100I

Validation StatusSupported

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Reslit

Overview

Paper Information3

Mixed infections in genotypic drug-resistant Mycobacterium tuberculosis.

Protein Change: T100I
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: genotypic resistance prediction using TB-Profiler software
Source Database: Reslit

Multi- and Extensively Drug Resistant Mycobacterium tuberculosis in South Africa: a Molecular Analysis of Historical Isolates.

A convolutional neural network highlights mutations relevant to antimicrobial resistance in Mycobacterium tuberculosis.

Protein Change: T100I
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: DeepLIFT saliency analysis and in silico introduction of mutations
Source Database: Reslit

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