ResLit - Antimicrobial Resistance Gene & Mutation Database

GenegyrA

Protein ChangeT500N

Nucleotide ChangeC1501A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fluoroquinolones
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Whole-genome sequencing for surveillance of fluoroquinolone resistance in rifampicin-susceptible tuberculosis in a rural district of Shanghai: A 10-year retrospective study.

PMID 36187694 · 2022

Mutations in gyrA were associated with fluoroquinolone resistance in Mycobacterium tuberculosis.

Mutation Information

gyrA: p.T500N / c.C1501A

Protein Change: T500N
Nucleotide Change: C1501A
Organisms: Mycobacterium tuberculosis
Confers Resistance To: fluoroquinolones
Validation Method: whole-genome sequencing
Source Database: Reslit

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