Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

GenegyrA

Protein ChangeD90A

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder DatabaseReslit

Overview

Mechanism: Target modification, DNA gyrase subunit A GyrA
Resistance To: levofloxacin|moxifloxacin, nalidixic acid|ciprofloxacin, quinolones
Organisms: Mycobacterium tuberculosis, Campylobacter jejuni, Campylobacter coli
Papers: 3

Paper Information3

1

Epidemiological cut-offs for Sensititre susceptibility testing of Mycobacterium tuberculosis: interpretive criteria cross validated with whole genome sequencing.

PMID 31974497 · 2020

Mutation Information

Protein Change: D90A
Organisms: Mycobacterium tuberculosis
Confers Resistance To: levofloxacin|moxifloxacin
Validation Method: whole genome sequencing and MIC testing
Source Database: Reslit

2

Cloning and nucleotide sequence of the Campylobacter jejuni gyrA gene and characterization of quinolone resistance mutations.

PMID 8384814 · 1993

gyrA

Mutation Information

Protein Change: D90A
Organisms: Campylobacter jejuni, Campylobacter coli
Confers Resistance To: nalidixic acid|ciprofloxacinquinolones
Effect on Function: Target modification; DNA gyrase subunit A GyrA
Source Database: ResFinder DatabaseReference Gene Catalog

3

Mechanisms of fluoroquinolone and macrolide resistance in Campylobacter spp.

PMID 16713726 · 2006

Mutation Information

Protein Change: D90A
Organisms: Campylobacter jejuni, Campylobacter coli
Confers Resistance To: nalidixic acid|ciprofloxacin
Effect on Function: Target modification
Source Database: ResFinder Database

Comments (0)

No comments yet. Be the first to comment!