ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeI470M

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder Database

Overview

Mechanism: Target modification, DNA topoisomerase IV subunit B ParE
Resistance To: nalidixic acid|ciprofloxacin, quinolones
Organisms: Escherichia coli
Papers: 1

Paper Information1

Prevalence of quinolone resistance mechanisms and associations to minimum inhibitory concentrations in quinolone-resistant Escherichia coli isolated from humans and swine in Denmark.

PMID 18500921 · 2008

Unknown phenotype if I470M occurs alone. Nalidixic acid and ciprofloxacin resistance when associated with gyrA mutations

Mutation Information

parE: p.I470M

Protein Change: I470M
Organisms: Escherichia coli
Confers Resistance To: nalidixic acid|ciprofloxacin
Effect on Function: Target modification
Source Database: ResFinder Database

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