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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations acrBF617A

GeneacrB

Acriflavin resistance protein B

Protein ChangeF617A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: macrolides|fluoroquinolones
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Effect of site-directed mutations in multidrug efflux pump AcrB examined by quantitative efflux assays.

PMID 27789287 · 2016

mutations in distal binding pocket of AcrB affect efflux of substrates

Mutation Information

Protein Change: F617A
Organisms: Escherichia coli
Confers Resistance To: macrolides|fluoroquinolones
Validation Method: site-directed mutagenesis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research