ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeS305R

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder DatabaseReslit

Overview

Mechanism: Target modification, two-component system sensor histidine kinase PmrB
Resistance To: polymyxin b|colistin, colistin
Organisms: Salmonella enterica
Papers: 2

Paper Information2

Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria.

Mutations in pmrB lead to constitutive activation of the pmrA/pmrB system, resulting in increased resistance to polymyxins.

pmrB

Genetic analysis of colistin resistance in Salmonella enterica serovar Typhimurium.

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