Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Shared and Unique Evolutionary Trajectories to Ciprofloxacin Resistance in Gram-Negative Bacterial Pathogens.
Mutations in gyrA are responsible for ciprofloxacin resistance in E. coli, A. baumannii, and P. aeruginosa.
Impeding pathways of intrinsic resistance in Escherichia coli confers antibiotic sensitization and resistance proofing.
gyrA mutation leads to nalidixic acid resistance
A novel, double mutation in DNA gyrase A of Escherichia coli conferring resistance to quinolone antibiotics.
The presence of Asp82Gly or Gly81Asp alone led to low-level resistance to fluoroquinolones but not to nalidixic acid resistance. When both mutations were present, resistance to both nalidixic acid and fluoroquinolones was expressed.
D82G mutation confers resistance to ciprofloxacin only. If D82G and G81D are present simultaneously, there is also nalidixic acid resistance
gyrA
Phenotypic and genotypic characterization of food animal isolates of Salmonella with reduced sensitivity to ciprofloxacin.
Mechanisms of quinolone resistance in Escherichia coli and Salmonella: recent developments.
gyrA
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