ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeD71G

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: single resistance variant, DNA gyrase subunit A GyrA
Resistance To: fluoroquinolones, quinolones
Organisms: Clostridioides difficile
Papers: 1

Paper Information1

Characterizations of clinical isolates of clostridium difficile by toxin genotypes and by susceptibility to 12 antimicrobial agents, including fidaxomicin (OPT-80) and rifaximin: a multicenter study in Taiwan.

PMID 22508299 · 2012

Clostridioides difficile gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003995

gyrA

Mutation Information

gyrA: p.D71G

Protein Change: D71G
Organisms: Clostridioides difficile
Confers Resistance To: fluoroquinolonesquinolones
Effect on Function: single resistance variant; DNA gyrase subunit A GyrA
Source Database: Card DatabaseReference Gene Catalog

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