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Browse Mutations gyrAC245T

GenegyrA

Protein ChangeC245T

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: fluoroquinolones
Organisms: Clostridioides difficile
Papers: 1

Paper Information1

1

Diversity of moxifloxacin resistance during a nosocomial outbreak of a predominantly ribotype ARU 027 Clostridium difficile diarrhea.

PMID 19818865 · 2009

Clostridioides difficile gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003995

Mutation Information

Protein Change: C245T
Organisms: Clostridioides difficile
Confers Resistance To: fluoroquinolones
Effect on Function: single resistance variant
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research