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Browse Mutations gyrBR136H

GenegyrB

Protein ChangeR136H

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB
Resistance To: aminocoumarin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

gyrB mutations which confer coumarin resistance also affect DNA supercoiling and ATP hydrolysis by Escherichia coli DNA gyrase.

PMID 1323022 · 1992

Escherichia coli gyrB conferring resistance to aminocoumarin; CARD accession: CARD:3003303

Mutation Information

Protein Change: R136H
Organisms: Escherichia coli
Confers Resistance To: aminocoumarin
Effect on Function: single resistance variant
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research