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Browse Mutations gyrBN502D

GenegyrB

Protein ChangeN502D

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: fluoroquinolones
Organisms: Mycobacterium leprae
Papers: 1

Paper Information1

1

Impact of amino acid substitutions in B subunit of DNA gyrase in Mycobacterium leprae on fluoroquinolone resistance.

PMID 23071850 · 2012

Mycobacterium leprae gyrB conferring resistance to fluoroquinolones; CARD accession: CARD:3003304

Mutation Information

Protein Change: N502D
Organisms: Mycobacterium leprae
Confers Resistance To: fluoroquinolones
Effect on Function: single resistance variant
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research