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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations pbp2bA446T

penicillin-binding protein 2B

Protein ChangeA446T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: beta lactams
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

1

Long Persistence of a Streptococcus pneumoniae 23F Clone in a Cystic Fibrosis Patient.

PMID 28596991 · 2017

Mutation A446T is associated with penicillin resistance.

Mutation Information

Protein Change: A446T
Organisms: Streptococcus pneumoniae
Confers Resistance To: beta lactams
Validation Method: genomic analysis and sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research