ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeD500N

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: co-dependent single resistance variant
Resistance To: fluoroquinolones
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.

PMID 21300839 · 2011

Mycobacterium tuberculosis gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003295

Mutation Information

gyrA: p.D500N

Protein Change: D500N
Organisms: Mycobacterium tuberculosis
Confers Resistance To: fluoroquinolones
Effect on Function: co-dependent single resistance variant
Source Database: Card Database

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