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Browse Mutations katGS457I

GenekatG

Protein ChangeS457I

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: isoniazid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Molecular characterization of drug-resistant Mycobacterium tuberculosis isolates from Ontario, Canada.

PMID 19520719 · 2009

Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid; CARD accession: CARD:3003392

Mutation Information

Protein Change: S457I
Organisms: Mycobacterium tuberculosis
Confers Resistance To: isoniazid
Effect on Function: single resistance variant
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research