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Browse Mutations pncAF106L

GenepncA

Protein ChangeF106L

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReslit

Overview

Mechanism: single resistance variant
Resistance To: pza, pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 2

Paper Information2

1

Phylogenetic lineages of tuberculosis isolates and their association with patient demographics in Tanzania.

PMID 35931954 · 2022

Mutation Information

Protein Change: F106L
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pza
Validation Method: genomic sequencing
Source Database: Reslit

2

PMID 978-92-4-008241-0

Mycobacterium tuberculosis pncA mutations conferring resistance to pyrazinamide; CARD accession: CARD:3003394

Mutation Information

Protein Change: F106L
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Effect on Function: single resistance variant
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research