ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeD82N

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReslit

Overview

Mechanism: single resistance variant
Resistance To: moxifloxacin
Organisms: Mycoplasma genitalium, Mycoplasmoides genitalium
Papers: 2

Paper Information2

Mycoplasma genitalium antibiotic resistance-associated mutations in genital and extragenital samples from men-who-have-sex-with-men attending a STI clinic in Verona, Italy.

PMID 37065200 · 2023

clinically relevant

Mutation Information

parC: p.D82N

Protein Change: D82N
Organisms: Mycoplasma genitalium
Confers Resistance To: moxifloxacin
Validation Method: Sanger sequencing
Source Database: Reslit

Comparison of full gyrA, gyrB, parC and parE gene sequences between all Ureaplasma parvum and Ureaplasma urealyticum serovars to separate true fluoroquinolone antibiotic resistance mutations from non-resistance polymorphism.

PMID 19567408 · 2009

Mycoplasma genitalium parC mutations confers resistance to Moxifloxacin; CARD accession: CARD:3004630

Mutation Information

parC: p.D82N

Protein Change: D82N
Organisms: Mycoplasmoides genitalium
Confers Resistance To: moxifloxacin
Effect on Function: single resistance variant
Source Database: Card Database

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