ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeD434H

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: fluoroquinolones
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

Topoisomerase mutations that are associated with high-level resistance to earlier fluoroquinolones in Staphylococcus aureus have less effect on the antibacterial activity of besifloxacin.

PMID 21996946 · 2011

Staphylococcus aureus parE conferring resistance to fluoroquinolones; CARD accession: CARD:3003315

Mutation Information

parE: p.D434H

Protein Change: D434H
Organisms: Staphylococcus aureus
Confers Resistance To: fluoroquinolones
Effect on Function: single resistance variant
Source Database: Card Database

Comments (0)

No comments yet. Be the first to comment!

Mutation Information

Browse AMR Mutations

Mutation Information