Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

GenepmrB

Protein ChangeA226T

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: associated with stable resistance, two-component system sensor histidine kinase PmrB
Resistance To: colistin
Organisms: Acinetobacter baumannii
Papers: 4

Paper Information4

1

Colistin Heteroresistance and Involvement of the PmrAB Regulatory System in Acinetobacter baumannii.

PMID 29914966 · 2018

mutated in pmrB gene

Mutation Information

Protein Change: A226T
Organisms: Acinetobacter baumannii
Confers Resistance To: colistin
Effect on Function: associated with stable resistance
Validation Method: sequencing and population analysis profiling
Source Database: Reslit

2

Rapid detection of colistin resistance in Acinetobacter baumannii using MALDI-TOF-based lipidomics on intact bacteria.

PMID 30442963 · 2018

Mutation Information

Protein Change: A226T
Organisms: Acinetobacter baumannii
Confers Resistance To: colistin
Validation Method: whole genome sequencing
Source Database: Reslit

3

Correlation between overexpression and amino acid substitution of the PmrAB locus and colistin resistance in Acinetobacter baumannii.

PMID 21497062 · 2011

pmrB

Mutation Information

Protein Change: A226T
Organisms: Acinetobacter baumannii
Confers Resistance To: colistin
Effect on Function: two-component system sensor histidine kinase PmrB
Source Database: Reference Gene Catalog

4

Sanford C. Barnum, discoverer of the rubber dam.

PMID 346095 · 1977

pmrB

Mutation Information

Protein Change: A226T
Organisms: Acinetobacter baumannii
Confers Resistance To: colistin
Effect on Function: two-component system sensor histidine kinase PmrB
Source Database: Reference Gene Catalog

Comments (0)

No comments yet. Be the first to comment!