ResLit - Antimicrobial Resistance Gene & Mutation Database

GenepmrB

Protein ChangeR263L

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: two-component system sensor histidine kinase PmrB
Resistance To: colistin
Organisms: Acinetobacter baumannii
Papers: 2

Paper Information2

Interplay between Colistin Resistance, Virulence and Fitness in Acinetobacter baumannii.

PMID 29160808 · 2017

Mutation Information

pmrB: p.R263L

Protein Change: R263L
Organisms: Acinetobacter baumannii
Confers Resistance To: colistin
Validation Method: experimental validation in clinical isolates
Source Database: Reslit

Emergence of colistin-resistance in extremely drug-resistant Acinetobacter baumannii containing a novel pmrCAB operon during colistin therapy of wound infections.

PMID 23812239 · 2013

pmrB

Mutation Information

pmrB: p.R263L

Protein Change: R263L
Organisms: Acinetobacter baumannii
Confers Resistance To: colistin
Effect on Function: two-component system sensor histidine kinase PmrB
Source Database: Reference Gene Catalog

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