ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeF60L

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: DNA topoisomerase IV subunit A ParC
Resistance To: ciprofloxacin|levofloxacin, quinolones
Organisms: Acinetobacter baumannii, Escherichia coli
Papers: 2

Paper Information2

Mutation-based fluoroquinolone resistance in carbapenem-resistant Acinetobacter baumannii and Escherichia coli isolates causing catheter-related bloodstream infections.

PMID 37151743 · 2023

Mutation Information

parC: p.F60L

Protein Change: F60L
Organisms: Acinetobacter baumannii, Escherichia coli
Confers Resistance To: ciprofloxacin|levofloxacin
Validation Method: DNA sequencing
Source Database: Reslit

Prevalence of quinolone resistance mechanisms and associations to minimum inhibitory concentrations in quinolone-resistant Escherichia coli isolated from humans and swine in Denmark.

PMID 18500921 · 2008

parC

Mutation Information

parC: p.F60L

Protein Change: F60L
Organisms: Escherichia coli
Confers Resistance To: quinolones
Effect on Function: DNA topoisomerase IV subunit A ParC
Source Database: Reference Gene Catalog

Comments (0)

No comments yet. Be the first to comment!

Mutation Information

Mutation Information

Browse AMR Mutations

Mutation Information

Mutation Information