ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeG78K

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: DNA topoisomerase IV subunit A ParC
Resistance To: quinolones
Organisms: Escherichia coli
Papers: 1

Paper Information1

Patterns of mutations in target genes in septicemia isolates of Escherichia coli and Klebsiella pneumoniae with resistance or reduced susceptibility to ciprofloxacin.

PMID 14510643 · 2003

parC

Mutation Information

parC: p.G78K

Protein Change: G78K
Organisms: Escherichia coli
Confers Resistance To: quinolones
Effect on Function: DNA topoisomerase IV subunit A ParC
Source Database: Reference Gene Catalog

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